Saturday’s contest that pits the Cleveland Guardians (92-68) versus the Houston Astros (87-73) at Progressive Field should be a competitive matchup based on our computer prediction, which projects a final score of 4-3 in favor of the Guardians. Game time is at 6:10 p.m. ET on Sept. 28.

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Guardians vs. Astros Matchup Info

• When: Saturday, September 28, 2024 at 6:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

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Guardians vs. Astros Predictions

• Score Prediction: Guardians 4, Astros 3
• Total Prediction: Under 8.5 runs

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Guardians vs. Astros Betting Lines

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Guardians Betting Insights

• Cleveland has won 64, or 64%, of the 100 contests it has been named as the odds-on favorite in this year.
• This season, the Guardians have come away with a win 51 times in 76 chances when named as a favorite of at least -125 or shorter on the moneyline.
• Cleveland’s games have gone over the total in 69 of 160 opportunities.
• The Guardians had a 6-5 record in the 11 games they were a moneyline favorite over their last 15 matchups.
• In its past 15 matchups — all had a set run total — Cleveland and its opponents combined to hit the over on the total three times.

Astros Betting Insights

• Houston has gone 20-22 in games it was the underdog on the moneyline (winning 47.6% of those games).
• The Astros have a 9-9 record (winning 50% of their games) when they have played as a moneyline underdog of +105 or longer.
• Houston has played in 160 games with an over/under set, and it has combined with opponents to go over the total 65 times (65-88-7).
• The Astros have played as underdogs in four of their past 15 games and won two of those contests.
• In its past 15 games with a total, Houston and its opponents have combined to hit the over six times.

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Guardians vs. Astros Probable Pitchers

Guardians’ Starting Pitcher: Ben Lively

• The 32-year-old has pitched to a 3.80 ERA this season with 7 strikeouts per nine innings compared to 2.8 walks per nine across 28 games.
• Ben Lively’s team is 14-4 this season when he starts and they are the moneyline favorite.
• Lively’s team has won 18 of his 28 starts this season.
• In Lively’s 28 starts with a total, the teams have hit the over 10 times.

Astros’ Starting Pitcher: Justin Verlander

• The 41-year-old has put together a 5.55 ERA and 7.4 strikeouts per nine innings in 16 games this season, while giving up a batting average of .272 to opposing batters.
• The Astros have been the moneyline underdog in four of Verlander’s starts this season, and they went 1-3 in those matchups.
• Verlander’s team has a 6-10 record over his 16 starts.
• Verlander’s starts with a set total this season have hit the over in seven of 16 games.

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Guardians’ 2024 Performance

Astros’ 2024 Performance

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