Friday’s contest at Oracle Park has the San Francisco Giants (79-80) taking on the St. Louis Cardinals (81-78) at 10:15 p.m. ET (on Sept. 27). Our computer prediction projects a narrow 4-3 victory for the Giants, so expect a competitive matchup.

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Giants vs. Cardinals Matchup Info

• When: Friday, September 27, 2024 at 10:15 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to Watch on TV: NBCS-BA
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

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Giants vs. Cardinals Predictions

• Score Prediction: Giants 4, Cardinals 3
• Total Prediction: Under 7.5 runs

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Giants vs. Cardinals Betting Lines

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Giants Betting Insights

• San Francisco has been the favorite in 74 games this season, and has come away with the win 42 times (56.8%) in those contests.
• This season, the Giants have come away with a win 31 times in 54 chances when named as a favorite of at least -130 or better on the moneyline.
• San Francisco’s games have gone over the total in 80 of 158 opportunities.
• In the past 15 games, the Giants were listed as the moneyline favorite by oddsmakers only two times, and they won both games.
• Over its past 15 matchups (all had set totals), San Francisco combined with its opponents to hit the over on the run total eight times.

Cardinals Betting Insights

• St. Louis has compiled a 40-40 record in games it was listed as the moneyline underdog (winning 50% of those games).
• The Cardinals have gone 15-23 in games they have played as a moneyline underdog with odds of +110 or longer (39.5%).
• St. Louis has had an over/under set by oddsmakers 158 times, and it has combined with opponents to go over the total in 71 of those games (71-81-6).
• In five games as underdogs in their past 15 matchups, the Cardinals have a record of 2-3.
• In its past 15 games with a total, St. Louis and its opponents have combined to hit the over four times.

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Giants vs. Cardinals Probable Pitchers

Giants’ Starting Pitcher: Landen Roupp

• The 26-year-old has pitched to a 2.70 ERA this season with 8.3 strikeouts per nine innings compared to 4.6 walks per nine across 22 games.
• Landen Roupp has yet to start a game this season when his team was the moneyline favorite.
• Roupp’s team has won one of his three starts this season.
• In Roupp’s three starts with a total, the teams have hit the over one time.

Cardinals’ Starting Pitcher: Miles Mikolas

• The 36-year-old has an ERA of 5.35, with 6.4 strikeouts per nine innings in 31 games this season. Opponents have a .283 batting average against him.
• The Cardinals have been the underdog on the moneyline in 22 of Mikolas’ starts this season, and they went 12-10 in those games.
• Mikolas’ team has a 15-16 record in his starts this season.
• Mikolas’ starts with a set total this season have hit the over in 14 of 31 contests.

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Giants’ 2024 Performance

Cardinals’ 2024 Performance

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