The Cleveland Guardians and Jose Ramirez will hit the field against the Houston Astros and Jose Altuve on Friday at 7:10 p.m. ET, in the first of a three-game series at Progressive Field.

Curious what a same game parlay might look like for the Guardians-Astros contest? Keep scrolling — we’ve got you covered with the key details ahead.

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Guardians vs. Astros Prediction & Pick

  • Score Prediction: Guardians 5, Astros 4
  • Expected Runs: 8.2

Guardians vs. Astros Odds

  • The Guardians vs Astros moneyline has Cleveland as a -120 favorite, while Houston is a +102 underdog on the road.
  • An over/under of 8 has been set for Guardians-Astros on Sept. 27, with the over being -105 and the under -115.

A potential way to build a same game parlay is to select a strikeout over/under prop of either team’s starting pitcher. Here’s a look at what’s available:

  • The Guardians’ Joey Cantillo has a strikeout over/under of 4.5 at +116 for the over and -148 for the under.
  • For the Astros, Ronel Blanco has a strikeout total of 4.5 at -108 for the over and -118 for the under.

Guardians vs. Astros Stats

  • The Guardians have won 65.6% of the games this season when they were the moneyline favorite (61-32).
  • This season, the Astros have been the underdog 39 times and won 19, or 48.7%, of those games.
  • Cleveland has played in 158 games with set over/under, and have combined with opponents to go over the total 70 times (70-80-8).
  • Houston and its opponents have gone over the total this season in 65 of its 159 opportunities.
Joey Cantillo (CLE) Pitcher Ronel Blanco (HOU)
2 – 3 W/L 12 – 6
35 IP 162.1
4.63 ERA 2.88
1.200 WHIP 1.103
9.5 K/9 9.0
3.3 BB/9 3.7

Guardians vs. Astros Same Game Parlay Payout

If you pick the Guardians — the computer favorite above — on the moneyline, choose the over per the computer prediction, and score a successful parlay, here’s the amount a $10 bet could net based the pitcher prop you tab:

  • Joey Cantillo over 4.5 strikeouts: $67.31
  • Joey Cantillo under 4.5 strikeouts: $49.98
  • Ronel Blanco over 4.5 strikeouts: $58.94
  • Ronel Blanco under 4.5 strikeouts: $56.13

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