Wednesday’s contest at Chase Field has the Arizona Diamondbacks (87-71) going head to head against the San Francisco Giants (79-79) at 9:40 p.m. ET (on Sept. 25). Our computer prediction projects a close 5-4 win for the Diamondbacks, so it should be a tight matchup.

Place your bets on any MLB matchup at BetMGM, and sign up with our link for a first-time deposit bonus!

Diamondbacks vs. Giants Matchup Info

• When: Wednesday, September 25, 2024 at 9:40 p.m. ET
• Where: Chase Field in Phoenix, Arizona
• How to Watch on TV: ARID
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

MLB is back on Apple TV+! Watch two live games every week, daily coverage, and more.

Diamondbacks vs. Giants Predictions

• Score Prediction: Diamondbacks 5, Giants 4
• Total Prediction: Over 8.5 runs

Bet on this or any MLB matchup at BetMGM

Diamondbacks vs. Giants Betting Lines

Get tickets for any MLB game this season at Ticketmaster!

Diamondbacks Betting Insights

• Arizona has won 50, or 61%, of the 82 contests it has been named as the odds-on favorite in this year.
• The Diamondbacks have been listed as a favorite of -230 or more on two occasions this season and won both games.
• Contests involving Arizona have gone over the total set by bookmakers in 90 of 158 chances this season.
• The Diamondbacks played as the moneyline favorite in 12 of their past 15 games, and they finished 6-6 in those matchups.
• Over its past 15 matchups, Arizona and its opponents combined to hit the over nine times (all 15 of the games had set totals).

Giants Betting Insights

• San Francisco has been the underdog on the moneyline 79 total times this season. It has finished 34-45 in those games.
• The Giants have played as a moneyline underdog of +190 or longer in only two games this season, which they lost both.
• San Francisco has had an over/under set by oddsmakers 157 times, and it has combined with opponents to go over the total in 79 of those games (79-70-8).
• The Giants have played as underdogs in 13 of their past 15 games and went 7-6 in those contests.
• In its past 15 games with a total, San Francisco and its opponents have failed to hit the over seven times.

Catch MLB action all season long on ESPN+!

Diamondbacks vs. Giants Probable Pitchers

Diamondbacks’ Starting Pitcher: Zac Gallen

• The 29-year-old has an ERA of 3.74, a 2.79 strikeout-to-walk ratio and a WHIP of 1.289 in 27 games this season.
• Zac Gallen’s team has won 61.9% of his starts when they are favored on the moneyline (13-8).
• Gallen’s team has won 17 of his 27 starts.
• In games Gallen has started this season, the teams are 15-11-1 at hitting the over.

Giants’ Starting Pitcher: Mason Black

• In eight games this season, the 24-year-old has an ERA of 5.88, with 7.5 strikeouts per nine innings. Opponents are batting .297 against him.
• The Giants have been the moneyline underdog in five of Black’s starts this season, and they went 2-3 in those games.
• Over Black’s seven starts, his team is 3-4.
• Black’s starts with a set total this season have gone over the run total in two of seven games.

Rep your team with officially licensed MLB gear! Head to Fanatics to find jerseys, shirts, and much more.

Diamondbacks’ 2024 Performance

Giants’ 2024 Performance

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.