Wednesday’s contest between the Cleveland Guardians (91-67) and the Cincinnati Reds (76-82) at Progressive Field is expected to be a competitive matchup, as our computer prediction projects a final score of 5-4, with the Guardians coming out on top. First pitch is at 6:40 p.m. ET on Sept. 25.

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Guardians vs. Reds Matchup Info

• When: Wednesday, September 25, 2024 at 6:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

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Guardians vs. Reds Predictions

• Score Prediction: Guardians 5, Reds 4
• Total Prediction: Over 8 runs

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Guardians vs. Reds Betting Lines

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Guardians Betting Insights

• Cleveland has won 63, or 64.3%, of the 98 contests it has been named as the odds-on favorite in this year.
• This season, the Guardians have come away with a win 23 times in 37 chances when named as a favorite of at least -148 or better on the moneyline.
• Cleveland and its opponents have hit the over in 69 of 158 games with a total set by oddsmakers this season.
• The Guardians were favored on the moneyline for 11 of their past 15 games, and they went 7-4 in those matchups.
• Over its past 15 outings (all 15 of them had set totals), Cleveland and its opponents combined to go over the run total three times.

Reds Betting Insights

• Cincinnati has compiled a 40-47 record in games it was listed as the moneyline underdog (winning 46% of those games).
• When playing as a moneyline underdog with odds of +124 or longer, the Reds have a record of 16-18 (47.1%).
• In the 157 games oddsmakers have set an over/under for Cincinnati, it has combined with opponents to go over the total 73 times (73-76-8).
• The Reds have played as underdogs in 12 of their past 15 games and went 6-6 in those contests.
• In its past 15 games with a total, Cincinnati and its opponents have combined to hit the over six times.

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Guardians vs. Reds Probable Pitchers

Guardians’ Starting Pitcher: Joey Cantillo

• The 24-year-old has pitched in eight games this season with an ERA of 4.63, a 2.85 strikeout-to-walk ratio and a WHIP of 1.200.
• Joey Cantillo’s team is 2-0 this season when he starts and they’re favored on the moneyline.
• In games Cantillo has started, his team is 4-3.
• Out of Cantillo’s seven starts with a total this season, two have hit the over.

Reds’ Starting Pitcher: Jakob Junis

• The 32-year-old has amassed an ERA of 2.61, with 7 strikeouts per nine innings in 23 games this season. Opposing hitters have a .201 batting average against him.
• The Reds were named the moneyline underdog for three Jakob Junis starts this season — they lost every game.
• Junis’ team has won one of his five starts.
• Junis has started five games with a total this season. His team has gone under in each of them.

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Guardians’ 2024 Performance

Reds’ 2024 Performance

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