Sunday’s game between the San Diego Padres (89-66) and the Chicago White Sox (36-119) at PETCO Park has a projected final score of 5-3 based on our computer prediction, with a favored Padres squad securing the victory. Game time is at 4:10 p.m. ET on Sept. 22.

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Padres vs. White Sox Matchup Info

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Padres vs. White Sox Predictions

  • Score Prediction: Padres 5, White Sox 3
  • Total Prediction: Over 8 runs

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Padres vs. White Sox Betting Lines

Padres vs White Sox Betting Information
Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds
Padres -325 +260 8 -112 -108

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Padres Betting Insights

  • San Diego has been the favorite in 97 games this season, and has come away with the win 56 times (57.7%) in those contests.
  • The Padres have played as a favorite of -325 or more just one time this year and came away with a win in that game.
  • San Diego and its opponents have hit the over in 80 of 155 games with a total set by oddsmakers this season.
  • The Padres went 8-5 over the 13 games they were a moneyline favorite in their past 15 matchups.
  • Over its past 15 outings — all had a set run total — San Diego and its opponents combined to hit the over on the total five times.

White Sox Betting Insights

  • Chicago has won 32 of the 147 games it was listed as the moneyline underdog this season (21.8%).
  • The White Sox have a 2-7 record (winning just 22.2% of their games) when they have played as a moneyline underdog of +260 or longer.
  • Chicago has played in 154 games with an over/under set, and it has combined with opponents to go over the total 65 times (65-80-9).
  • In 15 games as underdogs in their past 15 matchups, the White Sox had a record of 5-10.
  • Chicago and its opponents have combined to hit the over five times in its past 15 games with a total.

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Padres vs. White Sox Probable Pitchers

Padres’ Starting Pitcher: Yu Darvish

  • The 38-year-old has pitched in 14 games this season with an ERA of 3.21, a 3.42 strikeout-to-walk ratio and a WHIP of 1.114.
  • Yu Darvish’s team has a record of 5-2 this season when he starts and they are the favorite on the moneyline.
  • Darvish’s team has won 10 of his 14 starts this season.
  • Games started by Darvish have a 10-4-0 record at hitting the over this season.

White Sox’s Starting Pitcher: Sean Burke

  • In two games this season, he has a 2.25 ERA and 9 strikeouts per nine innings while opponents are batting .242 against him.
  • The White Sox were named the moneyline underdog for one Sean Burke start this season — they won.
  • His team has won the only matchup he’s made an appearance in this season.
  • Burke’s lone start with a total this season went under.

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Padres’ 2024 Performance

Split Record
Overall 89-66
Home 44-36
Road 45-30
One-Run Games 22-18
Scoring 5+ Runs 64-8

White Sox’s 2024 Performance

Split Record
Overall 36-119
Home 20-58
Road 16-61
One-Run Games 11-30
Scoring 5+ Runs 22-18

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