Saturday’s game between the San Diego Padres (88-66) and Chicago White Sox (36-118) squaring off at PETCO Park has a projected final score of 6-3 (according to our computer prediction) in favor of the Padres, who is listed as the favorite by our model. The game will start at 8:40 p.m. ET on Sept. 21.

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Padres vs. White Sox Matchup Info

• When: Saturday, September 21, 2024 at 8:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to Watch on TV: NBCS-CHI
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

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Padres vs. White Sox Predictions

• Score Prediction: Padres 6, White Sox 3
• Total Prediction: Over 8 runs

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Padres vs. White Sox Betting Lines

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Padres Betting Insights

• San Diego has come away with 55 wins in the 96 contests it has been listed as the favorite in this season.
• The Padres have played as a favorite of -298 or more just one time this year and came away with a win in that game.
• San Diego’s games have gone over the total in 80 of 154 opportunities.
• The Padres played as the moneyline favorite in 13 of their past 15 games, and they went 8-5 in those matchups.
• Over its past 15 outings (all 15 of them had set totals), San Diego and its opponents combined to go over the run total five times.

White Sox Betting Insights

• Chicago is 32-114 in games it was the underdog on the moneyline (winning 21.9% of those games).
• When they have played as a moneyline underdog with odds of +240 or longer, the White Sox have gone 2-10 (16.7%).
• In the 153 games bookmakers have set an over/under for Chicago, it has combined with opponents to go over the total 65 times (65-80-8).
• In 15 games as underdogs in their past 15 matchups, the White Sox had a record of 5-10.
• In its past 15 games with a total, Chicago and its opponents have combined to hit the over five times.

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Padres vs. White Sox Probable Pitchers

Padres’ Starting Pitcher: Martín Pérez

• The 33-year-old has an ERA of 4.36 and 7 strikeouts per nine innings, with a batting average against of .283 in 24 games this season.
• Martin Perez’s team has been victorious in 54.5% of the games he’s started as the moneyline favorite with a record of 6-5.
• Pérez’s team has a 13-11 record in his starts this season.
• In Pérez’s 24 starts with a total, the teams have hit the over 11 times.

White Sox’s Starting Pitcher: Chris Flexen

• The 30-year-old has an ERA of 5.09, with 6.8 strikeouts per nine innings in 31 games this season. Opponents are hitting .283 against him.
• The White Sox have been the underdog on the moneyline in 28 of Flexen’s starts this season, and they went 4-24 in those matchups.
• Flexen’s team has a 4-24 record in his starts this season.
• Flexen’s starts hit the over on the run total 15 times in 28 games with a set total this season.

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Padres’ 2024 Performance

White Sox’s 2024 Performance

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