Wednesday’s contest features the San Diego Padres (86-66) and the Houston Astros (82-69) matching up at PETCO Park in what is expected to be a competitive matchup, with a projected 5-4 victory for the Padres according to our computer prediction. Game time is at 6:40 p.m. ET on Sept. 18.

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Padres vs. Astros Matchup Info

• When: Wednesday, September 18, 2024 at 6:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to Watch on TV: SCHN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

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Padres vs. Astros Predictions

• Score Prediction: Padres 5, Astros 4
• Total Prediction: Over 7.5 runs

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Padres vs. Astros Betting Lines

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Padres Betting Insights

• San Diego has won 54, or 56.8%, of the 95 contests it has been named as the odds-on favorite in this year.
• This year, the Padres have won 43 of 77 games when listed as at least -122 or better on the moneyline.
• San Diego’s games have gone over the total in 80 of 152 opportunities.
• The Padres had an 8-5 record in the 13 games they were a moneyline favorite over their last 15 matchups.
• In its past 15 outings — all had a set run total — San Diego and its opponents combined to hit the over on the total six times.

Astros Betting Insights

• Houston has gone 19-21 in games it was listed as the moneyline underdog (winning 47.5% of those games).
• The Astros are 10-10 (winning 50% of their games) when playing as a moneyline underdog of +102 or longer.
• Houston has played in 151 games with a set over/under, and it has combined with opponents to go over the total 61 times (61-84-6).
• In the past 15 games, the Astros have been underdogs twice and split those games 1-1.
• When it comes to hitting the over, Houston and its opponents are 8-7-0 in its past 15 games with a total.

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Padres vs. Astros Probable Pitchers

Padres’ Starting Pitcher: Dylan Cease

• The 28-year-old has an ERA of 3.58 and 11 strikeouts per nine innings, with a batting average against of .204 in 31 games this season.
• When Dylan Cease starts a game and his team is the favorite on the moneyline, they have a record of 17-11.
• In games Cease has started, his team is 19-12.
• Games Cease has started this season hit the over 16 times in 31 chances.

Astros’ Starting Pitcher: Framber Valdez

• The 30-year-old has put together a 2.91 ERA and 8.7 strikeouts per nine innings over 26 games this season, while allowing a batting average of .217 to his opponents.
• The Astros have been the moneyline underdog in five of Valdez’s starts this season, and they went 3-2 in those games.
• Valdez’s team has an 18-8 record over his 26 starts.
• Valdez’s starts went over the run total eight times in 26 games with a set total this season.

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Padres’ 2024 Performance

Astros’ 2024 Performance

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