Wednesday’s contest between the St. Louis Cardinals (76-75) and Pittsburgh Pirates (71-80) matching up at Busch Stadium has a projected final score of 5-4 (according to our computer prediction) in favor of the Cardinals, so expect a competitive matchup. The game will begin at 7:45 p.m. ET on Sept. 18.

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Cardinals vs. Pirates Matchup Info

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Cardinals vs. Pirates Predictions

  • Score Prediction: Cardinals 5, Pirates 4
  • Total Prediction: Over 8 runs

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Cardinals vs. Pirates Betting Lines

Cardinals vs Pirates Betting Information
Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds
Cardinals -198 +164 8 -110 -110

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Cardinals Betting Insights

  • St. Louis has come away with 35 wins in the 70 contests it has been listed as the favorite in this season.
  • This season, the Cardinals have come away with a win one time in four chances when named as a favorite of at least -198 or better on the moneyline.
  • St. Louis’ games have gone over the total in 68 of 150 opportunities.
  • The Cardinals were the moneyline favorite in four of their past 15 games, and they went 3-1 in those matchups.
  • In its past 15 matchups — all had a set run total — St. Louis and its opponents combined to go over the total five times.

Pirates Betting Insights

  • Pittsburgh has a 34-51 record in games it was listed as the moneyline underdog (winning 40% of those games).
  • The Pirates have a 2-9 record (winning only 18.2% of their games) when playing as a moneyline underdog of +164 or longer.
  • In the 151 games oddsmakers have set an over/under for Pittsburgh, it has combined with opponents to go over the total 72 times (72-74-5).
  • In four games over their past 15 matchups when set as underdogs by sportsbooks, the Pirates had a record of 1-3.
  • Pittsburgh and its opponents have combined to hit the over seven times in its past 15 games with a total.

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Cardinals vs. Pirates Probable Pitchers

Cardinals’ Starting Pitcher: Sonny Gray

  • The 34-year-old has pitched in 27 games this season with an ERA of 3.75, a 5 strikeout-to-walk ratio and a WHIP of 1.071.
  • Sonny Gray’s team is 14-8 this season when he starts and they are the moneyline favorite.
  • Gray’s team has a 16-11 record in his starts this season.
  • Games Gray has started this season hit the over 11 times in 27 chances.

Pirates’ Starting Pitcher: Jake Woodford

  • Jake Woodford never pitched as a moneyline underdog a season ago.

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Cardinals’ 2024 Performance

Split Record
Overall 76-75
Home 41-35
Road 35-40
One-Run Games 27-20
Scoring 5+ Runs 44-12

Pirates’ 2024 Performance

Split Record
Overall 71-80
Home 38-40
Road 33-40
One-Run Games 23-26
Scoring 5+ Runs 44-18

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