Monday’s game at PETCO Park has the San Diego Padres (85-65) taking on the Houston Astros (81-68) at 9:40 p.m. ET (on Sept. 16). Our computer prediction projects a close 5-4 victory for the Padres, so expect a tight matchup.

Place your bets on any MLB matchup at BetMGM, and sign up with our link for a first-time deposit bonus!

Padres vs. Astros Matchup Info

• When: Monday, September 16, 2024 at 9:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to Watch on TV: SDPA
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

MLB is back on Apple TV+! Watch two live games every week, daily coverage, and more.

Padres vs. Astros Predictions

• Score Prediction: Padres 5, Astros 4
• Total Prediction: Over 7.5 runs

Bet on this or any MLB matchup at BetMGM

Padres vs. Astros Betting Lines

Get tickets for any MLB game this season at Ticketmaster!

Padres Betting Insights

• San Diego has been the favorite in 93 games this season, and has come away with the win 53 times (57%) in those contests.
• The Padres have a win-loss record of 41-31 when favored by -125 or better by bookmakers this year.
• San Diego and its opponents have gone over in 80 of 150 games with a total set by sportsbooks this season.
• The Padres were the moneyline favorite in 11 of their past 15 games, and they finished 7-4 in those matchups.
• Over its past 15 outings (all had set totals), San Diego combined with its opponents to hit the over on the run total seven times.

Astros Betting Insights

• Houston has won 18 of the 38 games it was the underdog on the moneyline this season (47.4%).
• When playing as a moneyline underdog with odds of +105 or longer, the Astros have a 9-8 record (winning 52.9% of their games).
• Houston has had an over/under set by bookmakers 149 times, and it has combined with opponents to go over the total in 61 of those games (61-82-6).
• The Astros are not favored for the first time in quite a while, as they have not been an underdog in their past 15 games.
• In its past 15 games with a total, Houston and its opponents have failed to hit the over seven times.

Catch MLB action all season long on ESPN+!

Padres vs. Astros Probable Pitchers

Padres’ Starting Pitcher: Yu Darvish

• The 38-year-old has pitched in 13 games this season with a 3.52 ERA and 8.7 strikeouts per nine innings with a batting average against of .233.
• Yu Darvish’s team has won 66.7% of his starts when they are favored on the moneyline (4-2).
• Darvish’s team is 9-4 when he starts this season.
• In Darvish’s 13 starts with a total, the teams have hit the over 10 times.

Astros’ Starting Pitcher: Spencer Arrighetti

• In 26 games this season, the 24-year-old has an ERA of 4.72, with 10.8 strikeouts per nine innings. Opponents are batting .249 against him.
• The Astros have a 3-5 record in Arrighetti’s eight starts this season when they were the underdog on the moneyline.
• Arrighetti’s team is 10-16 in his 26 starts.
• Arrighetti’s starts hit the over on the run total 10 times in 26 games with a set total this season.

Rep your team with officially licensed MLB gear! Head to Fanatics to find jerseys, shirts, and much more.

Padres’ 2024 Performance

Astros’ 2024 Performance

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.