Wednesday’s game at Guaranteed Rate Field has the Cleveland Guardians (83-62) squaring off against the Chicago White Sox (33-113) at 2:10 p.m. ET. Our computer prediction projects a 6-4 victory for the Guardians, who are a slight favorite based on our model.

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Guardians vs. White Sox Matchup Info

• When: Wednesday, September 11, 2024 at 2:10 p.m. ET
• Where: Guaranteed Rate Field in Chicago, Illinois
• How to Watch on TV: NBCS-CHI
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• Tickets: Get tickets for this game at Ticketmaster

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Guardians vs. White Sox Predictions

• Score Prediction: Guardians 6, White Sox 4
• Total Prediction: Over 8 runs

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Guardians vs. White Sox Betting Lines

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Guardians Betting Insights

• Cleveland has come away with 58 wins in the 89 contests it has been listed as the favorite in this season.
• This season, the Guardians have been victorious four times in six chances when named as a favorite of at least -230 or better on the moneyline.
• Cleveland’s games have gone over the total in 66 of 145 opportunities.
• The Guardians went 6-3 across the nine games they were a moneyline favorite in their past 15 matchups.
• Over its past 15 matchups (all 15 of them had set totals), Cleveland and its opponents combined to hit the over three times.

White Sox Betting Insights

• Chicago has a 29-109 record in games it was listed as the moneyline underdog (winning 21% of those games).
• The White Sox have a 10-35 record (winning only 22.2% of their games) when they have played as a moneyline underdog of +190 or longer.
• Chicago has combined with opponents to go over the total 62 times this season for a 62-75-8 record against the over/under.
• The White Sox have played as underdogs in 15 of their past 15 games and won two of those contests.
• In its past 15 games with a total, Chicago and its opponents have failed to hit the over 11 times.

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Guardians vs. White Sox Probable Pitchers

Guardians’ Starting Pitcher: Matthew Boyd

• The 33-year-old has pitched to a 2.20 ERA this season with 8.2 strikeouts per nine innings compared to 1.6 walks per nine across five games.
• Matthew Boyd’s team has been victorious in 66.7% of the games he’s started as the moneyline favorite with a record of 2-1.
• Boyd’s team is 4-1 when he starts this season.
• Out of Boyd’s five starts with a total this season, one has hit the over.

White Sox’s Starting Pitcher: Davis Martin

• The 27-year-old has an ERA of 3.29, with 8.2 strikeouts per nine innings in eight games this season. Opposing batters have a .233 batting average against him.
• The White Sox were named the moneyline underdog for seven Davis Martin starts this season — they lost every time.
• Martin’s seven starts have all ended in a loss for his team this season.
• Martin’s starts went over the run total two times in seven games with a set total this season.

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Guardians’ 2024 Performance

White Sox’s 2024 Performance

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