Wednesday’s game between the San Diego Padres (76-58) and the St. Louis Cardinals (65-67) at Busch Stadium is expected to be a close matchup, as our computer prediction projects a final score of 5-4, with the Padres taking home the win. First pitch is at 7:45 p.m. ET on August 28.

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Padres vs. Cardinals Matchup Info

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Padres vs. Cardinals Predictions

  • Score Prediction: Padres 5, Cardinals 4
  • Total Prediction: Under 8.5 runs

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Padres vs. Cardinals Betting Lines

Padres vs Cardinals Betting Information
Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds
Padres -130 +110 8.5 -103 -126

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Padres Betting Insights

  • San Diego has won 46, or 56.8%, of the 81 contests it has been named as the odds-on favorite in this year.
  • The Padres have a mark of 36-26 in contests where oddsmakers favor them by -130 or better on the moneyline.
  • Contests involving San Diego have gone over the total set by bookmakers in 73 of 134 chances this season.
  • The Padres were the moneyline favorite in 13 of their past 15 games, and they finished 8-5 in those matchups.
  • Over its past 15 outings (all had set totals), San Diego combined with its opponents to go over the run total nine times.

Cardinals Betting Insights

  • St. Louis has won 49.2% of the games this season it was the underdog on the moneyline (32-33).
  • When playing as a moneyline underdog with odds of +110 or longer, the Cardinals have an 11-20 record (winning only 35.5% of their games).
  • St. Louis has played in 131 games with a set over/under, and it has combined with its opponents to go over the total 61 times (61-65-5).
  • The Cardinals have played as underdogs in nine of their past 15 games and won four of those contests.
  • In its past 15 games with a total, St. Louis and its opponents are 6-9-0 when it comes to hitting the over.

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Padres vs. Cardinals Probable Pitchers

Padres’ Starting Pitcher: Joe Musgrove

  • The 31-year-old has pitched in 13 games this season with a 4.43 ERA and 8.3 strikeouts per nine innings with a batting average against of .266.
  • Joe Musgrove’s team is 5-4 this season when he starts and they are the moneyline favorite.
  • Musgrove’s team has an 8-5 record in his starts this season.
  • Games started by Musgrove have a 6-7-0 record at hitting the over this season.

Cardinals’ Starting Pitcher: Andre Pallante

  • In 23 games this season, the 25-year-old has amassed an ERA of 3.84, with 6.7 strikeouts per nine innings. Opponents are hitting .241 against him.
  • The Cardinals have been the underdog on the moneyline in nine of Pallante’s starts this season, and they went 4-5 in those matchups.
  • Pallante’s team is 7-7 in his 14 starts.
  • Andre Pallante has started 14 contests with a total set by sportsbooks this season. The teams have combined to go over the run total in five of them.

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Padres’ 2024 Performance

Split Record
Overall 76-58
Home 37-32
Road 39-26
One-Run Games 18-14
Scoring 5+ Runs 57-7

Cardinals’ 2024 Performance

Split Record
Overall 65-67
Home 34-32
Road 31-35
One-Run Games 23-18
Scoring 5+ Runs 40-12

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