On the Week 1 Football Bowl Subdivision schedule, we have the over/under for the Akron vs. Ohio State matchup as the best bet on the card. Scroll down for more tips on point spreads and totals, including parlay opportunities.

Get computer predictions and insights for that game and more below.

Place your bets on any college football matchup at BetMGM. Sign up today using our link.

College Football Computer Picks – Best Spread Bets

Watch college football this season on Fubo and ESPN+.

Pick: Troy -8.5 vs. Nevada

• Matchup: Nevada Wolf Pack at Troy Trojans
• Projected Winner & Margin: Troy by 34.7 points
• Time: 7:00 PM ET
• Date: August 31
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Pick: Ohio +17.5 vs. Syracuse

• Matchup: Ohio Bobcats at Syracuse Orange
• Projected Winner & Margin: Ohio by 4.4 points
• Time: 3:30 PM ET
• Date: August 31
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: James Madison -9.5 vs. Charlotte

• Matchup: James Madison Dukes at Charlotte 49ers
• Projected Winner & Margin: James Madison by 28.4 points
• Time: 8:00 PM ET
• Date: August 31
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: South Alabama -5.5 vs. North Texas

• Matchup: North Texas Mean Green at South Alabama Jaguars
• Projected Winner & Margin: South Alabama by 19.5 points
• Time: 5:00 PM ET
• Date: August 31
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Pick: Wyoming +7 vs. Arizona State

• Matchup: Wyoming Cowboys at Arizona State Sun Devils
• Projected Winner & Margin: Wyoming by 5.9 points
• Time: 10:30 PM ET
• Date: August 31
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Use these spread picks at BetMGM today!

College Football Computer Picks – Best Total Bets

Under 58.5 – Akron vs. Ohio State

• Matchup: Akron Zips at Ohio State Buckeyes
• Projected Total: 43 points
• Time: 3:30 PM ET
• Date: August 31
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo

Over 64.5 – LSU vs. USC

• Matchup: LSU Tigers at USC Trojans
• Projected Total: 74.5 points
• Time: 7:30 PM ET
• Date: September 1
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 46.5 – Notre Dame vs. Texas A&M

• Matchup: Notre Dame Fighting Irish at Texas A&M Aggies
• Projected Total: 55.4 points
• Time: 7:30 PM ET
• Date: August 31
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 49.5 – Southern Miss vs. Kentucky

• Matchup: Southern Miss Golden Eagles at Kentucky Wildcats
• Projected Total: 57.6 points
• Time: 7:45 PM ET
• Date: August 31
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 48.5 – Virginia Tech vs. Vanderbilt

• Matchup: Virginia Tech Hokies at Vanderbilt Commodores
• Projected Total: 56.2 points
• Time: 12:00 PM ET
• Date: August 31
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Take advantage of our picks and place your bet at BetMGM today!

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.